Mutagenesis Pregabalin was not mutagenic in bacteria or in mammalian cells in vitro, was not clastogenic in mammalian units in vitro As well as in vivo, and didn't induce unscheduled DNA synthesis in mouse or rat hepatocytes.Impairment of Fertility In fertility reports wherein male rats were orally administered pregabalin (fifty to 2500 mg/kg) prio